Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 5/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14996549 | 0.86 | PTGS1 (0.46) | CNR2LMNACNR1SIGMAR1OPRM1 | |
| SCHEMBL9906369 | 0.81 | CNR2 (0.44) | CNR2LMNACNR1L3MBTL1PRKCZ | |
| SCHEMBL14996637 | 0.80 | LMNA (0.50) | CNR2LMNACNR1SIGMAR1OPRM1 | |
| SCHEMBL3685546 | 0.80 | KDM4E (0.51) | CNR2LMNACNR1SIGMAR1OPRM1 | |
| SCHEMBL14314274 | 0.79 | PRKCZ (0.55) | PRKCZ | |
| SCHEMBL14996548 | 0.78 | LMNA (0.48) | CNR2LMNACNR1SIGMAR1OPRM1 | |
| SCHEMBL1028147 | 0.75 | LMNA (0.46) | CNR2LMNACNR1OPRM1L3MBTL1 | |
| SCHEMBL14996676 | 0.75 | SIGMAR1 (0.57) | CNR2LMNACNR1SIGMAR1OPRM1 | |
| SCHEMBL12859469 | 0.75 | PTGS1 (0.43) | CNR2LMNACNR1OPRM1L3MBTL1 | |
| SCHEMBL1831047 | 0.74 | RPA1 (0.68) | LMNACNR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008003770-A1 | PHENYL SUBSTITUTED HETEROARYL-DERIVATIVES AND USE THEREOF AS ANTI-TUMOR AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-10 | — | — | WO | disclosed |