Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | REN | P00797 | 15/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CTSE | P14091 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432038 | 0.89 | MASP2 (0.38) | CA2 | |
| SCHEMBL3141449 | 0.84 | REN (0.43) | CA2RENCTSDCTSE | |
| SCHEMBL3141428 | 0.84 | REN (0.43) | CA2RENCTSDCTSE | |
| SCHEMBL3141442 | 0.84 | REN (0.43) | CA2RENCTSDCTSE | |
| SCHEMBL3141433 | 0.84 | REN (0.43) | CA2RENCTSDCTSE | |
| SCHEMBL1433593 | 0.83 | MASP2 (0.35) | CA2RENBACE1 | |
| SCHEMBL1432234 | 0.82 | MASP2 (0.42) | — | |
| SCHEMBL3153410 | 0.81 | REN (0.48) | CA2RENCTSDCTSECTSS | |
| SCHEMBL3153397 | 0.81 | REN (0.48) | CA2RENCTSDCTSECTSS | |
| SCHEMBL3153401 | 0.81 | REN (0.48) | CA2RENCTSDCTSECTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |