Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | REN | P00797 | 7/20 | 0.34 |
| ▸ | PPIB | P23284 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | FURIN | P09958 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432038 | 0.92 | MASP2 (0.38) | MASP2CYP3A4PPIBCA1CA2 | |
| SCHEMBL1432127 | 0.83 | CA2 (0.42) | RENBACE1CA2 | |
| SCHEMBL1901982 | 0.82 | MASP2 (0.39) | MASP2PPIBFURINNAMPT | |
| SCHEMBL1432234 | 0.80 | MASP2 (0.42) | MASP2PPIBNAMPT | |
| SCHEMBL1432104 | 0.79 | CYP3A4 (0.38) | MASP2CYP3A4RENPPIBBACE1 | |
| SCHEMBL1431623 | 0.79 | MASP2 (0.41) | MASP2PPIBFURINNAMPT | |
| SCHEMBL1906629 | 0.79 | HPGD (0.39) | MASP2 | |
| SCHEMBL1432321 | 0.77 | MASP2 (0.38) | MASP2PPIBNAMPT | |
| SCHEMBL1432168 | 0.75 | MASP2 (0.35) | MASP2CYP3A4CA1CA2FURIN | |
| SCHEMBL1901133 | 0.74 | MASP2 (0.39) | MASP2PPIBNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |