Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PPIB | P23284 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | FCER2 | P06734 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901133 | 0.89 | MASP2 (0.39) | MASP2F2PRSS1PPIBF10 | |
| SCHEMBL1432234 | 0.84 | MASP2 (0.42) | MASP2F2PRSS1PPIBF10 | |
| SCHEMBL1432321 | 0.84 | MASP2 (0.38) | MASP2F2PRSS1PPIBF10 | |
| SCHEMBL1431623 | 0.82 | MASP2 (0.41) | MASP2F2PRSS1PPIBF10 | |
| SCHEMBL1906629 | 0.82 | HPGD (0.39) | MASP2F2PRSS1ALDH1A1LMNA | |
| SCHEMBL3141550 | 0.82 | PSMB5 (0.43) | MASP2F2PRSS1MMP1FCER2 | |
| SCHEMBL3141538 | 0.82 | PSMB5 (0.43) | MASP2F2PRSS1MMP1FCER2 | |
| SCHEMBL3141543 | 0.82 | PSMB5 (0.43) | MASP2F2PRSS1MMP1FCER2 | |
| SCHEMBL1432698 | 0.81 | DPP4 (0.38) | MASP2CPB1 | |
| SCHEMBL1901982 | 0.81 | MASP2 (0.39) | MASP2F2PRSS1PPIBF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |