Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 3/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | MASP2 | O00187 | 3/20 | 0.37 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 2/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432219 | 0.92 | EHMT2 (0.51) | EHMT2NAMPTCCR2MASP2 | |
| SCHEMBL1431927 | 0.92 | EHMT2 (0.51) | EHMT2NAMPTCCR2MASP2 | |
| SCHEMBL1432565 | 0.90 | EHMT2 (0.45) | EHMT2NAMPTCCR2TLR2MASP2 | |
| SCHEMBL1431965 | 0.89 | EHMT2 (0.43) | EHMT2NAMPTCCR2TLR2MASP2 | |
| SCHEMBL1432580 | 0.86 | CCR2 (0.45) | EHMT2CCR2MASP2TRPV1 | |
| SCHEMBL1432256 | 0.86 | CCR2 (0.45) | EHMT2CCR2MASP2TRPV1 | |
| SCHEMBL1432418 | 0.85 | CHRNA1 (0.41) | EHMT2MASP2TRPV1CHRNB2SLC6A2 | |
| SCHEMBL1433112 | 0.85 | KCNQ2 (0.42) | EHMT2SCN5ASCN9ACCR2TRPV1 | |
| SCHEMBL1432137 | 0.82 | EHMT2 (0.44) | EHMT2SCN5ASCN9ANAMPTTLR2 | |
| SCHEMBL1432213 | 0.78 | EHMT2 (0.47) | EHMT2NAMPTMASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |