Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MASP2 | O00187 | 3/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432565 | 0.99 | EHMT2 (0.45) | EHMT2KCNQ2PDPK1NPC1MASP2 | |
| SCHEMBL1431927 | 0.89 | EHMT2 (0.51) | EHMT2MASP2NAMPTCCR2 | |
| SCHEMBL1432219 | 0.89 | EHMT2 (0.51) | EHMT2MASP2NAMPTCCR2 | |
| SCHEMBL1432142 | 0.89 | EHMT2 (0.46) | EHMT2NPC1MASP2NAMPTTLR2 | |
| SCHEMBL1432418 | 0.86 | CHRNA1 (0.41) | EHMT2KCNQ2MASP2 | |
| SCHEMBL1432580 | 0.85 | CCR2 (0.45) | EHMT2MASP2CCR2 | |
| SCHEMBL1432256 | 0.85 | CCR2 (0.45) | EHMT2MASP2CCR2 | |
| SCHEMBL1431876 | 0.84 | MASP2 (0.43) | EHMT2PDPK1MASP2NAMPTTLR2 | |
| SCHEMBL1902464 | 0.84 | MASP2 (0.39) | PDPK1MASP2NAMPTTLR2CACNA1G | |
| SCHEMBL1899812 | 0.84 | MASP2 (0.39) | PDPK1MASP2NAMPTTLR2CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |