Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 9/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432256 | 0.90 | CCR2 (0.45) | CCR2EHMT2TACR1TRPV1 | |
| SCHEMBL1432580 | 0.90 | CCR2 (0.45) | CCR2EHMT2TACR1TRPV1 | |
| SCHEMBL1432418 | 0.88 | CHRNA1 (0.41) | KCNQ2EHMT2TRPV1 | |
| SCHEMBL1432565 | 0.85 | EHMT2 (0.45) | KCNQ2CCR2EHMT2TACR1TRPV1 | |
| SCHEMBL1432142 | 0.85 | EHMT2 (0.46) | CCR2EHMT2SCN5ASCN9ATRPV1 | |
| SCHEMBL1432382 | 0.84 | F2 (0.40) | KCNQ2F2CCR2TACR1 | |
| SCHEMBL1431965 | 0.84 | EHMT2 (0.43) | KCNQ2CCR2EHMT2 | |
| SCHEMBL1431927 | 0.84 | EHMT2 (0.51) | CCR2EHMT2 | |
| SCHEMBL1432219 | 0.84 | EHMT2 (0.51) | CCR2EHMT2 | |
| SCHEMBL1432197 | 0.84 | F2 (0.40) | KCNQ2F2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |