Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.81 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.75 |
| ▸ | HTR2C | P28335 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | PPARG | P37231 | 2/20 | 0.72 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.72 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.72 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.72 |
| ▸ | ALB | P02768 | 1/20 | 0.72 |
| ▸ | PGR | P06401 | 3/20 | 0.71 |
| ▸ | DAO | P14920 | 1/20 | 0.69 |
| ▸ | SNCA | P37840 | 1/20 | 0.69 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.69 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.62 |
| ▸ | APEX1 | P27695 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14331136 | 1.00 | KMT2A (0.81) | KMT2ANR1I2HTR2CMAPTPPARG | |
| SCHEMBL14321878 | 1.00 | KMT2A (0.81) | KMT2ANR1I2HTR2CMAPTPPARG | |
| SCHEMBL14321875 | 1.00 | KMT2A (0.81) | KMT2ANR1I2HTR2CMAPTPPARG | |
| SCHEMBL23043566 | 0.90 | NR1I2 (0.77) | KMT2ANR1I2HTR2CMAPTPPARG | |
| SCHEMBL23051167 | 0.90 | NR1I2 (0.77) | KMT2ANR1I2HTR2CMAPTPPARG | |
| Ceftiofur SCHEMBL332042 | 0.90 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG | |
| Ceftiofur SCHEMBL12727853 | 0.90 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG | |
| Ceftiofur SCHEMBL332041 | 0.90 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG | |
| Ceftiofur SCHEMBL9367220 | 0.90 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG | |
| Ceftiofur SCHEMBL10296647 | 0.90 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120329770-A1 | CEPHALOSPORIN DERIVATIVES USEFUL AS BETA-LACTAMASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | DMITRIENKO GARY IGOR (CA) | 2012-12-27 | — | — | US | disclosed |
| US-20120329770-A1 | CEPHALOSPORIN DERIVATIVES USEFUL AS BETA-LACTAMASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | DMITRIENKO GARY IGOR (CA) | 2012-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329770-A1 | CEPHALOSPORIN DERIVATIVES USEFUL AS BETA-LACTAMASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CMBL, PEPD, BCHE | KMT2A 2026/4885NR1I2 3438/4885HTR2C 3175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.