Sr-144528

Sr-144528

SCHEMBL8137029

Cc1ccc(Cn2nc(C(=O)N[C@@H]3C(C)(C)[C@@H]4CC[C@@]3(C)C4)cc2-c2ccc(Cl)c(C)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 18/20 1.00
▸ CNR1 P21554 6/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sr-144528 SCHEMBL1546003 1.00 CNR2 (1.00) CNR2CNR1
Sr-144528 SCHEMBL14355050 1.00 CNR2 (1.00) CNR2CNR1
Sr-144528 SCHEMBL8039660 1.00 CNR2 (1.00) CNR2CNR1
Sr-144528 SCHEMBL8313006 1.00 CNR2 (1.00) CNR2CNR1
Sr-144528 SCHEMBL19551517 1.00 CNR2 (1.00) CNR2CNR1
Sr-144528 SCHEMBL1432281 1.00 CNR2 (1.00) CNR2CNR1
SCHEMBL13883212 0.94 CNR2 (0.88) CNR2CNR1
SCHEMBL13926164 0.94 CNR2 (0.88) CNR2CNR1
SCHEMBL15377558 0.92 CNR2 (0.85) CNR2CNR1
SCHEMBL8042546 0.92 CNR2 (0.85) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4146345-A2 CANNABINOID RECEPTOR TYPE 2 (CB2) MODULATORS AND USES THEREOF Teon Therapeutics, Inc. (US) 2023-03-15 — — EP claimed
WO-2021226206-A2 CANNABINOID RECEPTOR TYPE 2 (CB2) MODULATORS AND USES THEREOF TEON THERAPEUTICS, INC. (US) 2021-11-11 — — WO claimed
US-20200289458-A1 TOPICAL FORMULATIONS OF CANNABINOIDS AND USE THEREOF IN THE TREATMENT OF PAIN INMED PHARMACEUTICALS INC (CA) 2020-09-17 — — US claimed
EP-3558281-A1 TREATMENT OF MENTAL, MOVEMENT AND BEHAVIORAL DISORDERS Anavi-Goffer, Sharon (IL) 2019-10-30 — — EP claimed
US-20190321355-A1 TREATMENT OF MENTAL, MOVEMENT AND BEHAVIORAL DISORDERS ANAVI GOFFER SHARON (IL) 2019-10-24 — — US claimed
US-20190142788-A1 USE OF TOPICAL FORMULATIONS OF CANNABINOIDS IN THE TREATMENT OF EPIDERMOLYSIS BULLOSA AND RELATED CONNECTIVE TISSUE DISORDERS INMED PHARMACEUTICALS INC. (CA) 2019-05-16 — — US claimed
EP-3452036-A1 USE OF TOPICAL FORMULATIONS OF CANNABINOIDS IN THE TREATMENT OF EPIDERMOLYSIS BULLOSA AND RELATED CONNECTIVE TISSUE DISORDERS Inmed Pharmaceuticals Inc. (CA) 2019-03-13 — — EP claimed
US-20190008845-A1 PROGRAM RANDOMIZATION FOR CYBER-ATTACK RESILIENT CONTROL IN PROGRAMMABLE LOGIC CONTROLLERS SIEMENS AKTIENGESELLSCHAFT (DE) 2019-01-10 — — US claimed
WO-2018112138-A1 TREATMENT OF MENTAL, MOVEMENT AND BEHAVIORAL DISORDERS ANAVI GOFFER SHARON (IL) 2018-06-21 — — WO claimed
WO-2017190249-A1 USE OF TOPICAL FORMULATIONS OF CANNABINOIDS IN THE TREATMENT OF EPIDERMOLYSIS BULLOSA AND RELATED CONNECTIVE TISSUE DISORDERS INMED PHARMACEUTICALS INC. (CA) 2017-11-09 — — WO claimed
EP-4727648-A1 CANNABINOID RECEPTOR 2 MODULATORS F. Hoffmann-La Roche AG (CH) 2026-04-22 — — EP disclosed
US-20250332180-A1 CANNABINOIDS AND IL-15 ACTIVATE NK CELLS UNIV CALIFORNIA (US) 2025-10-30 — — US disclosed
US-12357604-B2 Topical formulations of cannabinoids and use thereof in the treatment of pain INMED PHARMACEUTICALS INC. (CA) 2025-07-15 — — US disclosed
WO-2025090587-A1 CANNABINOIDS COMPOUNDS AND THEIR USE IN THE TREATMENT OF NEURONAL DISORDERS INMED PHARMACEUTICALS INC. (CA) 2025-05-01 — — WO disclosed
WO-2025090133-A1 COMPOSITIONS AND METHODS FOR USE OF CANNABINOL COMPOUNDS IN NEUROPROTECTION INMED PHARMACEUTICALS INC. (CA) 2025-05-01 — — WO disclosed
US-7763607-B2 Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2010-07-27 — — US disclosed
US-7763607-B2 Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2010-07-27 — — US disclosed
WO-2007125048-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING CBX CANNABINOID RECEPTOR MODULATORS AND POTASSIUM CHANNEL MODULATORS SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-08 — — WO disclosed
US-20070254862-A1 Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-01 — — US disclosed
US-20070254862-A1 Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190321355-A1 TREATMENT OF MENTAL, MOVEMENT AND BEHAVIORAL DISORDERS HTR2C, CNR1, HTR4 CNR2 4/4885CNR1 2/4885
US-12357604-B2 Topical formulations of cannabinoids and use thereof in the treatment of pain CNR2, CNR1, LCAT CNR2 1/4885CNR1 2/4885
US-20200289458-A1 TOPICAL FORMULATIONS OF CANNABINOIDS AND USE THEREOF IN THE TREATMENT OF PAIN CNR2, CNR1, LCAT CNR2 1/4885CNR1 2/4885
US-20070254862-A1 Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators CNR1, CNR2, KCNJ11 CNR2 2/4885CNR1 1/4885
US-20190008845-A1 PROGRAM RANDOMIZATION FOR CYBER-ATTACK RESILIENT CONTROL IN PROGRAMMABLE LOGIC CONTROLLERS CNR1, CNR2, HTR4 CNR2 2/4885CNR1 1/4885
US-20190142788-A1 USE OF TOPICAL FORMULATIONS OF CANNABINOIDS IN THE TREATMENT OF EPIDERMOLYSIS BULLOSA AND RELATED CONNECTIVE TISSUE DISORDERS KRT18, DSP, DSC1 CNR2 28/4885CNR1 60/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback