Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18100469 | 0.79 | BRD4 (0.47) | PDGFRAMAPK8CDK5CLK4ERAP1 | |
| SCHEMBL28257310 | 0.74 | ALDH1A1 (0.51) | PDGFRAMAPK8CDK5CLK4MAPT | |
| SCHEMBL30753514 | 0.72 | MAPT (0.48) | PDGFRAMAPK8CDK5CLK4ERAP1 | |
| SCHEMBL18919401 | 0.72 | MAPT (0.48) | PDGFRAMAPK8CDK5CLK4ERAP1 | |
| SCHEMBL4449250 | 0.72 | ERAP1 (0.68) | PDGFRAMAPK8CDK5CLK4ERAP1 | |
| SCHEMBL13961695 | 0.72 | PDGFRA (0.49) | PDGFRAMAPK8CDK5CLK4ERAP1 | |
| SCHEMBL27619559 | 0.70 | LMNA (0.48) | PDGFRAMAPK8CDK5CLK4MAPT | |
| SCHEMBL6294085 | 0.70 | LMNA (0.48) | PDGFRAMAPK8CDK5CLK4MAPT | |
| SCHEMBL28538536 | 0.69 | MCL1 (0.53) | PDGFRAMAPK8CDK5CLK4ERAP1 | |
| SCHEMBL12679823 | 0.69 | KCNA3 (0.47) | PDGFRAMAPK8CDK5CLK4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120329787-A1 | FUNGICIDAL PYRANONES AND OXAZINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-27 | — | — | US | claimed |
| US-20120329787-A1 | FUNGICIDAL PYRANONES AND OXAZINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329787-A1 | FUNGICIDAL PYRANONES AND OXAZINONES | PNPO, NOX1, NOXO1 | PDGFRA 4779/4885MAPK8 3673/4885CDK5 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.