Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 3/20 | 0.39 |
| ▸ | MASP2 | O00187 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431762 | 0.86 | MASP2 (0.43) | KLKB1MASP2BACE1BACE2PSMB1 | |
| SCHEMBL1902876 | 0.86 | BACE1 (0.40) | KLKB1MASP2BACE1BACE2PSMB1 | |
| SCHEMBL1432265 | 0.84 | PDPK1 (0.35) | MASP2BACE1 | |
| SCHEMBL3148337 | 0.84 | KLKB1 (0.51) | KLKB1MASP2PSMB1PSMB5PSMB2 | |
| SCHEMBL1432378 | 0.84 | KLKB1 (0.51) | KLKB1MASP2PSMB1PSMB5PSMB2 | |
| SCHEMBL1432369 | 0.83 | MASP2 (0.38) | MASP2BACE1 | |
| SCHEMBL1432248 | 0.83 | NAMPT (0.41) | MASP2BACE1BACE2 | |
| SCHEMBL1903992 | 0.81 | NAMPT (0.42) | MASP2 | |
| SCHEMBL1433148 | 0.81 | MASP2 (0.39) | KLKB1MASP2BACE1BACE2CTSD | |
| SCHEMBL1432287 | 0.81 | MASP2 (0.39) | KLKB1MASP2BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |