Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902876 | 0.94 | BACE1 (0.40) | NAMPTPDPK1MASP2HDAC1 | |
| SCHEMBL1901316 | 0.90 | CA2 (0.40) | PDPK1 | |
| SCHEMBL1905074 | 0.90 | NAMPT (0.43) | NAMPTEHMT2MASP2MEN1KMT2A | |
| SCHEMBL1907648 | 0.89 | BACE1 (0.44) | NAMPTMASP2CPB1 | |
| SCHEMBL1907783 | 0.89 | PDPK1 (0.38) | NAMPTPDPK1MASP2MEN1KMT2A | |
| SCHEMBL1903417 | 0.86 | EPHX2 (0.43) | PDPK1PTPN1 | |
| SCHEMBL1901450 | 0.85 | MAPT (0.36) | PDPK1MASP2KMT2AHDAC1 | |
| SCHEMBL1902464 | 0.85 | MASP2 (0.39) | NAMPTPDPK1MASP2TLR2 | |
| SCHEMBL1899812 | 0.85 | MASP2 (0.39) | NAMPTPDPK1MASP2TLR2 | |
| SCHEMBL1431762 | 0.84 | MASP2 (0.43) | NAMPTMASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |