Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MASP2 | O00187 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432651 | 0.89 | NAMPT (0.46) | NAMPTMASP2L3MBTL1EHMT2KMT2A | |
| SCHEMBL1432618 | 0.88 | NAMPT (0.41) | NAMPTMASP2L3MBTL1EHMT2KMT2A | |
| SCHEMBL1904701 | 0.85 | NAMPT (0.45) | NAMPTMASP2L3MBTL1EHMT2HPGD | |
| SCHEMBL1431865 | 0.85 | NAMPT (0.45) | NAMPTMASP2L3MBTL1EHMT2KMT2A | |
| SCHEMBL1904386 | 0.85 | NAMPT (0.45) | NAMPTMASP2L3MBTL1EHMT2KMT2A | |
| SCHEMBL1432011 | 0.85 | NAMPT (0.45) | NAMPTMASP2L3MBTL1EHMT2KMT2A | |
| SCHEMBL1431682 | 0.84 | MASP2 (0.40) | NAMPTMASP2KMT2ACPB2GAA | |
| SCHEMBL1432545 | 0.83 | NAMPT (0.44) | NAMPTMASP2L3MBTL1EHMT2KMT2A | |
| SCHEMBL1432462 | 0.83 | MASP2 (0.39) | NAMPTMASP2KMT2A | |
| SCHEMBL1432382 | 0.83 | F2 (0.40) | MASP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |