Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431810 | 0.92 | MASP2 (0.39) | MASP2MEN1KMT2ARECQLPSEN1 | |
| SCHEMBL1432462 | 0.90 | MASP2 (0.39) | MASP2MEN1KMT2ANAMPT | |
| SCHEMBL1431749 | 0.89 | MASP2 (0.40) | MASP2MEN1KMT2ARECQLPSEN1 | |
| SCHEMBL1432382 | 0.88 | F2 (0.40) | MASP2MEN1KMT2AROCK2 | |
| SCHEMBL1432449 | 0.84 | NAMPT (0.43) | MASP2KMT2ACPA1CPB2GAA | |
| SCHEMBL1900464 | 0.82 | MASP2 (0.41) | MASP2MEN1KMT2AGAANAMPT | |
| SCHEMBL1432197 | 0.80 | F2 (0.40) | MASP2MEN1KMT2AROCK2 | |
| SCHEMBL1431676 | 0.80 | CTSB (0.43) | MASP2 | |
| SCHEMBL3145950 | 0.80 | CTSB (0.43) | MASP2 | |
| SCHEMBL1432188 | 0.79 | MASP2 (0.39) | MASP2GAANAMPTROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |