SCHEMBL1926809

SCHEMBL1926809

CC(=O)N1c2ccc(C)cc2Sc2cc(C)cc(N)c21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOX1 Q9Y5S8 1/20 0.44
▸ SNCA P37840 3/20 0.41
▸ BCHE P06276 8/20 0.39
▸ HSD17B3 P37058 1/20 0.39
▸ NOTUM Q6P988 1/20 0.36
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ MAPT P10636 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ ALOX12 P18054 1/20 0.35
▸ ALOX15 P16050 2/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ TDP1 Q9NUW8 2/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ TP53 P04637 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ THRB P10828 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396465 0.87 BCHE (0.47) NOX1SNCABCHEMEN1KMT2A
SCHEMBL1828807 0.81 BCHE (0.37) BCHEKMT2AMAPTALDH1A1CYP3A4
SCHEMBL1207990 0.77 NOX1 (0.41) NOX1SNCABCHEMEN1KMT2A
SCHEMBL1208165 0.73 NOX1 (0.58) NOX1SNCABCHEMEN1KMT2A
SCHEMBL29850660 0.73 NOX1 (0.58) NOX1SNCABCHEMEN1KMT2A
SCHEMBL19398391 0.72 SNCA (0.76) NOX1SNCABCHEMEN1KMT2A
Ammonia Solution, Strong SCHEMBL1927787 0.72 NOX1 (0.56) NOX1SNCABCHEMEN1KMT2A
Hydrochloric Acid SCHEMBL1929442 0.72 NOX1 (0.56) NOX1SNCABCHEMEN1KMT2A
SCHEMBL18906407 0.71 BCHE (0.63) BCHEMEN1KMT2AMAPTHPGD
SCHEMBL17356855 0.71 BCHE (0.66) NOX1BCHEMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250222006-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2025-07-10 — — US disclosed
US-20240115580-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2024-04-11 — — US disclosed
US-11878021-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds WISTA LABORATORIES LTD. (SG) 2024-01-23 — — US disclosed
EP-3121169-B1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LAB LTD (SG) 2022-02-09 — — EP disclosed
US-20210322435-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS Wis Ta Laboratories Ltd. (SG) 2021-10-21 — — US disclosed
US-11045477-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds WISTA LABORATORIES LTD. (SG) 2021-06-29 — — US disclosed
US-20200261465-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2020-08-20 — — US disclosed
US-20180263999-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2018-09-20 — — US disclosed
US-9980971-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds WISTA LABORATORIES LTD. (SG) 2018-05-29 — — US disclosed
US-20170273986-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2017-09-28 — — US disclosed
US-20130317012-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2013-11-28 — — US disclosed
EP-2057136-B1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LAB LTD (SG) 2013-05-22 — — EP disclosed
US-8440821-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds WISTA LABORATORIES LTD. (SG) 2013-05-14 — — US disclosed
EP-2457904-A1 Methods of synthesis and/or purification of diaminophenothiazinium compounds Wista Laboratories Ltd. (SG) 2012-05-30 — — EP disclosed
EP-2457905-A1 Methods of synthesis and/or purification of diaminophenothiazinium compounds Wista Laboratories Ltd. (SG) 2012-05-30 — — EP disclosed
US-20110294795-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. 2011-12-01 — — US disclosed
US-7956183-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds WISTA LABORATORIES LTD. (SG) 2011-06-07 — — US disclosed
US-20090259040-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2009-10-15 — — US disclosed
EP-2057136-A2 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS Wista Laboratories Ltd. (SG) 2009-05-13 — — EP disclosed
WO-2008007074-A2 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS WISTA LABORATORIES LTD. (SG) 2008-01-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180263999-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885BCHE 1159/4885
US-20250222006-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885BCHE 1159/4885
US-20170273986-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885BCHE 1159/4885
US-20210322435-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885BCHE 1159/4885
US-11045477-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885BCHE 1159/4885
US-20090259040-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS PARK7, SNCA, GRN NOX1 3287/4885SNCA 2/4885BCHE 213/4885
US-20240115580-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885BCHE 1159/4885
US-20130317012-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MAPT, TPMT, UROD NOX1 4259/4885SNCA 227/4885BCHE 552/4885
US-11878021-B2 Methods of synthesis and/or purification of diaminophenothiazinium compounds MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885BCHE 1159/4885
US-20110294795-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MMAB, MB, ABCB7 NOX1 3149/4885SNCA 1425/4885BCHE 978/4885
US-20200261465-A1 METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS MB, TPMT, HBB NOX1 1655/4885SNCA 173/4885BCHE 1159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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