Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732306 | 0.76 | — | — | |
| SCHEMBL19732461 | 0.73 | CYP19A1 (0.37) | — | |
| SCHEMBL29796729 | 0.72 | NTRK1 (0.30) | — | |
| SCHEMBL18164732 | 0.65 | FOLH1 (0.42) | — | |
| SCHEMBL23978355 | 0.63 | CYP19A1 (0.56) | CA12CA1CA2CA9 | |
| SCHEMBL12990471 | 0.63 | KCNMA1 (0.55) | — | |
| SCHEMBL22307512 | 0.63 | NLRP3 (0.48) | — | |
| SCHEMBL15395877 | 0.60 | — | — | |
| SCHEMBL24135604 | 0.60 | — | — | |
| SCHEMBL11899559 | 0.58 | P2RX7 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338599-B2 | Compounds having a potentiating effect on the activity of ethionamide and uses thereof | INSTITUT PASTEUR DE LILLE (FR) | 2012-12-25 | — | — | US | disclosed |