Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 5/20 | 0.45 |
| ▸ | F2 | P00734 | 8/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432181 | 0.86 | F2 (0.60) | MASP2F2 | |
| SCHEMBL1431930 | 0.84 | MASP2 (0.45) | MASP2F2CTSCCTSLFNTA | |
| Hydrochloric Acid SCHEMBL1432057 | 0.83 | MASP2 (0.44) | MASP2F2CTSCCTSLFNTA | |
| SCHEMBL1432216 | 0.83 | MASP2 (0.44) | MASP2F2CTSCCTSLFNTA | |
| SCHEMBL1433144 | 0.81 | MASP2 (0.41) | MASP2F2CTSLFNTAPGGT1B | |
| SCHEMBL1434677 | 0.78 | HTRA1 (0.41) | MASP2KLKB1 | |
| SCHEMBL3157823 | 0.77 | MASP2 (0.44) | MASP2F2KLKB1 | |
| SCHEMBL1900640 | 0.77 | KLKB1 (0.43) | MASP2F2KLKB1 | |
| SCHEMBL3157804 | 0.77 | MASP2 (0.44) | MASP2F2KLKB1 | |
| SCHEMBL1900645 | 0.77 | KLKB1 (0.43) | MASP2F2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |