Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | FURIN | P09958 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431930 | 0.83 | MASP2 (0.45) | MASP2FNTAPGGT1BF2CTSL | |
| Hydrochloric Acid SCHEMBL1432057 | 0.82 | MASP2 (0.44) | MASP2FNTAPGGT1BF2CTSL | |
| SCHEMBL1432216 | 0.82 | MASP2 (0.44) | MASP2FNTAPGGT1BF2FURIN | |
| SCHEMBL1432661 | 0.81 | MASP2 (0.45) | MASP2FNTAPGGT1BF2KLKB1 | |
| SCHEMBL1431568 | 0.80 | TACR1 (0.44) | MASP2KLKB1P2RX7CTSL | |
| SCHEMBL1432060 | 0.78 | KLKB1 (0.42) | MASP2F2KLKB1FURINF7 | |
| SCHEMBL1434677 | 0.78 | HTRA1 (0.41) | MASP2KLKB1FURINF7NAMPT | |
| SCHEMBL1432067 | 0.78 | KLKB1 (0.42) | MASP2F2KLKB1FURINF7 | |
| SCHEMBL1431764 | 0.77 | FURIN (0.42) | MASP2F2KLKB1FURINF7 | |
| SCHEMBL3157823 | 0.77 | MASP2 (0.44) | MASP2F2KLKB1FURINF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |