Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 20/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 19/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1612779 | 0.96 | MTNR1B (0.69) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL1643499 | 0.92 | MTNR1B (0.66) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL1614142 | 0.88 | MTNR1A (0.42) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL13934405 | 0.86 | MTNR1A (0.57) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL10053045 | 0.85 | MTNR1B (0.56) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| SCHEMBL14493649 | 0.85 | MTNR1A (0.67) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| Ramelteon SCHEMBL29380213 | 0.79 | MTNR1A (1.00) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| (R)-Ramelteon SCHEMBL338730 | 0.79 | MTNR1A (1.00) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| (R)-Ramelteon SCHEMBL1566122 | 0.79 | MTNR1A (1.00) | MTNR1BMTNR1AABCB11SIGMAR1USP2 | |
| (R)-Ramelteon SCHEMBL29827337 | 0.79 | MTNR1A (1.00) | MTNR1BMTNR1AABCB11SIGMAR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2537842-A1 | Crystals of (S)-N-[2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethyl]propionamide | Takeda Pharmaceutical Company Limited (JP) | 2012-12-26 | — | — | EP | disclosed |