Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 6/20 | 0.54 |
| ▸ | KLK1 | P06870 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MASP2 | O00187 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1434866 | 0.90 | KLKB1 (0.53) | KLKB1KLK1TACR1CTSSCTSK | |
| SCHEMBL1433580 | 0.88 | KLKB1 (0.65) | KLKB1KLK1MASP2 | |
| SCHEMBL1434273 | 0.87 | F2 (0.50) | KLKB1CTSSCTSKMASP2 | |
| SCHEMBL1435041 | 0.87 | TACR1 (0.56) | KLKB1TACR1 | |
| SCHEMBL1434448 | 0.87 | KLKB1 (0.51) | KLKB1KLK1MASP2CYP3A4 | |
| SCHEMBL1433064 | 0.86 | KLKB1 (0.61) | KLKB1KLK1CTSSCTSKMASP2 | |
| SCHEMBL1433139 | 0.85 | KLKB1 (0.51) | KLKB1KLK1MASP2 | |
| SCHEMBL1433012 | 0.85 | KLKB1 (0.57) | KLKB1KLK1CTSSMASP2 | |
| SCHEMBL1433394 | 0.85 | KLKB1 (0.49) | KLKB1KLK1TACR1MASP2 | |
| SCHEMBL1901459 | 0.84 | OPRD1 (0.45) | KLKB1OPRD1TACR1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |