Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | MASP2 | O00187 | 3/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1434507 | 0.88 | TACR1 (0.53) | KLKB1 | |
| SCHEMBL1433013 | 0.87 | KLKB1 (0.54) | KLKB1MASP2CTSSCTSK | |
| SCHEMBL1433349 | 0.85 | F2 (0.51) | F2MASP2CTSS | |
| SCHEMBL1434232 | 0.84 | F2 (0.51) | F2KLKB1MASP2CTSSCTSK | |
| SCHEMBL1433111 | 0.82 | F2 (0.53) | F2KLKB1MASP2 | |
| SCHEMBL1434709 | 0.81 | F2 (0.51) | F2KLKB1MASP2 | |
| SCHEMBL1434049 | 0.81 | KLKB1 (0.47) | F2KLKB1MASP2 | |
| SCHEMBL1433533 | 0.80 | PYGL (0.49) | F2CTSS | |
| SCHEMBL1433101 | 0.79 | CTSS (0.65) | F2MASP2PSMB8PSMB5CTSS | |
| SCHEMBL3157541 | 0.78 | F2 (0.58) | F2MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |