SCHEMBL14330856

SCHEMBL14330856

NCCCCCCOP(=O)(O)OP(=O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](Cn2cnc3c(N)ncnc32)CC1O

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TRPM2 O94759 2/20 0.62
▸ POLB P06746 1/20 0.53
▸ P2RY1 P47900 7/20 0.51
▸ P2RY2 P41231 2/20 0.51
▸ P2RX1 P51575 2/20 0.51
▸ P2RX3 P56373 2/20 0.51
▸ P2RX2 Q9UBL9 2/20 0.51
▸ SRC P12931 1/20 0.51
▸ P2RX4 Q99571 1/20 0.51
▸ ALDH1A1 P00352 1/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.51
▸ ENPP1 P22413 2/20 0.51
▸ DTYMK P23919 3/20 0.49
▸ MACROD2 A1Z1Q3 1/20 0.49
▸ SIRT6 Q8N6T7 1/20 0.49
▸ MACROD1 Q9BQ69 1/20 0.49
▸ PARG Q86W56 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21029886 0.89 POLB (0.61) TRPM2POLBP2RY1P2RY2P2RX1
SCHEMBL13111573 0.86 POLB (0.69) TRPM2POLBP2RY1P2RY2P2RX1
SCHEMBL10055622 0.86 POLB (0.69) TRPM2POLBP2RY1P2RY2P2RX1
SCHEMBL16280905 0.86 POLB (0.69) TRPM2POLBP2RY1P2RY2P2RX1
SCHEMBL13127042 0.86 POLB (0.69) TRPM2POLBP2RY1P2RY2P2RX1
SCHEMBL21030880 0.82 POLB (0.75) TRPM2POLBP2RY1P2RY2P2RX1
SCHEMBL14330854 0.80 POLB (0.51) TRPM2POLBP2RY2
SCHEMBL2167873 0.78 P2RY1 (0.84) TRPM2P2RY1P2RY2P2RX1P2RX3
SCHEMBL10055646 0.77 POLB (0.56) TRPM2POLBP2RY1P2RY2P2RX1
SCHEMBL16280904 0.77 POLB (0.56) TRPM2POLBP2RY1P2RY2P2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8999674-B2 Methods and apparatus for single molecule sequencing using energy transfer detection Life Technologies Corporation (US) 2015-04-07 — — US disclosed
US-20120329042-A1 METHODS AND APPARATUS FOR SINGLE MOLECULE SEQUENCING USING ENERGY TRANSFER DETECTION Life Technologies Corporation (US) 2012-12-27 — — US disclosed
Send feedback