Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | MASP2 | O00187 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | PPIB | P23284 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432571 | 0.91 | LCK (0.41) | TACR1MASP2ITGB1ITGA4PPIB | |
| SCHEMBL1432215 | 0.90 | TACR1 (0.45) | TACR1XIAPMASP2 | |
| SCHEMBL1432409 | 0.90 | CTSL (0.48) | CTSLITGB1ITGA4 | |
| SCHEMBL1432153 | 0.90 | TACR1 (0.43) | TACR1XIAPMASP2ITGB1ITGA4 | |
| SCHEMBL1432180 | 0.89 | DPP4 (0.40) | XIAPMASP2KLKB1PPIB | |
| SCHEMBL1431638 | 0.89 | DPP4 (0.40) | XIAPMASP2KLKB1PPIB | |
| Hydrochloric Acid SCHEMBL1432515 | 0.88 | DPP4 (0.40) | XIAPMASP2KLKB1PPIB | |
| SCHEMBL1432824 | 0.88 | MASP2 (0.41) | TACR1MASP2ITGB1ITGA4KLKB1 | |
| SCHEMBL1432349 | 0.88 | EPHX2 (0.45) | EPHX2P2RX7 | |
| SCHEMBL1432803 | 0.88 | CTSB (0.41) | MASP2CTSLITGB1ITGA4KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |