SCHEMBL1433258

SCHEMBL1433258

CCCCCNC1CCC1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.62
GNAO1 P09471 2/20 0.62
GNAI1 P63096 2/20 0.62
S1PR4 O95977 2/20 0.57
S1PR1 P21453 2/20 0.57
S1PR3 Q99500 2/20 0.57
S1PR5 Q9H228 1/20 0.57
EPHX1 P07099 11/20 0.52
EPHX2 P34913 2/20 0.46
GBA1 P04062 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28207776 0.98 GNAI3 (0.66) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL21367529 0.98 GNAI3 (0.66) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL28243190 0.98 GNAI3 (0.66) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL3959388 0.95 GNAI3 (0.62) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL24437800 0.93 GNAI3 (0.60) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL561543 0.93 GNAI3 (0.60) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL1485554 0.93 GNAI3 (0.66) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL3326405 0.93 GNAI3 (0.66) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL7778149 0.93 GNAI3 (0.60) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL9801263 0.93 GNAI3 (0.66) GNAI3GNAO1GNAI1S1PR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108602955-B Photocuring method, compound used in photocuring method, and composition 富士胶片和光纯药株式会社 2021-08-06 CN disclosed
CN-107848963-B Acid-resistant alkali-producing agent and/or radical-producing agent, and curable resin composition containing same 富士胶片和光纯药株式会社 2020-11-03 CN disclosed
US-10775388-B2 Methods of using antibodies to determine periostin levels in a sample MEDIMMUNE, LLC (US) 2020-09-15 US disclosed
CN-110678500-A Photo-or thermosetting method and curable resin composition 富士胶片和光纯药株式会社 2020-01-10 CN disclosed
CN-108602955-A The compound and composition used in process for photocuring, the process for photocuring 富士胶片和光纯药株式会社 2018-09-28 CN disclosed
US-20180196065-A1 NOVEL ASSAY TO DETECT HUMAN PERIOSTIN MEDIMMUNE, LLC 2018-07-12 US disclosed
CN-107848963-A Alkali-producing agent and/or radical-generating agent having acid resistance, and curable resin composition containing same 和光纯药工业株式会社 2018-03-27 CN disclosed
US-20110098300-A1 Compounds Comprising A Cyclobutoxy Group UCB PHARMA, S.A. (BE) 2011-04-28 US disclosed
EP-2300426-A1 COMPOUNDS COMPRISING A CYCLOBUTOXY GROUP UCB Pharma, S.A. (BE) 2011-03-30 EP disclosed
US-20100305116-A1 Compounds Comprising a Cyclobutoxy Group UCB PHARMA, S.A. (BE) 2010-12-02 US disclosed
US-20100292188-A1 Compounds Comprising A Cyclobutoxy Group UCB PHARMA S.A. (BE) 2010-11-18 US disclosed
EP-2238144-A1 COMPOUNDS COMPRISING A CYCLOBUTOXY GROUP UCB Pharma, S.A. (BE) 2010-10-13 EP disclosed
EP-2146980-A2 HISTAMINE H3 RECEPTOR LIGANDS COMPRISING A CYCLOBUTOXY GROUP UCB Pharma S.A. (BE) 2010-01-27 EP disclosed
WO-2009147149-A1 COMPOUNDS COMPRISING A CYCLOBUTOXY GROUP UCB PHARMA, S.A. (BE) 2009-12-10 WO disclosed
WO-2009092764-A1 COMPOUNDS COMPRISING A CYCLOBUTOXY GROUP UCB PHARMA, S.A. (BE) 2009-07-30 WO disclosed
WO-2008128919-A2 HISTAMINE H3 RECEPTOR LIGANDS COMPRISING A CYCLOBUTOXY GROUP UCB PHARMA S.A. (BE) 2008-10-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305116-A1 Compounds Comprising a Cyclobutoxy Group HMGCR, TECR, CYP4A11 GNAI3 3373/4885GNAO1 2653/4885GNAI1 3645/4885
US-20110098300-A1 Compounds Comprising A Cyclobutoxy Group CHAT, BACE1, GRIN2B GNAI3 1546/4885GNAO1 441/4885GNAI1 1461/4885
US-20100292188-A1 Compounds Comprising A Cyclobutoxy Group CYP11B2, CYP11B1, CYP4B1 GNAI3 1792/4885GNAO1 1280/4885GNAI1 1981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.