Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTMT1 | Q9BV86 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 3/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 2/20 | 0.37 |
| ▸ | MC1R | Q01726 | 2/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906955 | 1.00 | NTMT1 (0.44) | NTMT1TACR1FNTAPGGT1BP2RX7 | |
| SCHEMBL1904935 | 0.90 | TACR1 (0.41) | NTMT1TACR1DPP4 | |
| SCHEMBL1902611 | 0.90 | TACR1 (0.41) | NTMT1TACR1DPP4 | |
| SCHEMBL1903923 | 0.89 | TACR1 (0.41) | TACR1DPP4 | |
| SCHEMBL1908359 | 0.89 | TACR1 (0.41) | TACR1DPP4 | |
| SCHEMBL1433336 | 0.86 | TACR1 (0.46) | NTMT1TACR1FNTAPGGT1BP2RX7 | |
| SCHEMBL1906919 | 0.83 | CTSB (0.40) | CTSSCTSK | |
| SCHEMBL13623819 | 0.83 | F2 (0.52) | NTMT1TACR1P2RX7 | |
| SCHEMBL1432873 | 0.83 | F2 (0.52) | NTMT1TACR1P2RX7 | |
| SCHEMBL1901984 | 0.83 | MEN1 (0.39) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051673-A1 | AMINOTHIAZOLE DERIVATIVES USEFUL AS KLK1 INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |