Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | MASP2 | O00187 | 4/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432178 | 0.80 | F2 (0.51) | F2MASP2 | |
| SCHEMBL1433101 | 0.80 | CTSS (0.65) | F2MASP2CTSKCTSSCTSB | |
| SCHEMBL3157541 | 0.78 | F2 (0.58) | F2MASP2 | |
| SCHEMBL1433349 | 0.78 | F2 (0.51) | F2MASP2CTSS | |
| Hydrochloric Acid SCHEMBL3153046 | 0.77 | F2 (0.57) | F2MASP2 | |
| Hydrochloric Acid SCHEMBL1432141 | 0.77 | F2 (0.57) | F2MASP2 | |
| SCHEMBL1434273 | 0.77 | F2 (0.50) | F2MASP2CTSKCTSS | |
| SCHEMBL1431845 | 0.76 | MME (0.51) | MMEACECPA1ACE2MASP2 | |
| SCHEMBL13623819 | 0.75 | F2 (0.52) | F2MASP2 | |
| SCHEMBL1432873 | 0.75 | F2 (0.52) | F2MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |