Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14334666 | 0.85 | HTR6 (0.57) | HTR6 | |
| SCHEMBL14334868 | 0.83 | HTR6 (0.46) | HTR6MAOAMAOB | |
| SCHEMBL3718329 | 0.82 | HTR6 (0.46) | HTR6MAOAMAOB | |
| SCHEMBL14335098 | 0.81 | HTR6 (0.62) | HTR6HTR2CHTR2BHTR2A | |
| SCHEMBL14334647 | 0.81 | HTR6 (0.62) | HTR6MAOAMAOB | |
| SCHEMBL6295375 | 0.79 | HTR6 (0.57) | HTR6MAOAMAOB | |
| SCHEMBL14334882 | 0.77 | HTR6 (0.41) | HTR6 | |
| SCHEMBL5141633 | 0.77 | MAOA (0.56) | HTR6MAOAMAOB | |
| SCHEMBL6208847 | 0.77 | MAOA (0.56) | HTR6MAOAMAOB | |
| SCHEMBL14334461 | 0.76 | HTR6 (0.41) | HTR6MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304050-B2 | Antibacterial agents | PFIZER INC. (US) | 2007-12-04 | — | — | US | disclosed |