Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718323 | 0.86 | HTR6 (0.45) | HTR6F10MAOAMAOBDRD1 | |
| SCHEMBL14334868 | 0.86 | HTR6 (0.46) | HTR6MAOAMAOB | |
| SCHEMBL2183799 | 0.83 | F10 (0.50) | HTR6F10MAOAMAOB | |
| SCHEMBL2184137 | 0.83 | MAOA (0.55) | HTR6MAOAMAOB | |
| SCHEMBL2184129 | 0.83 | MAOA (0.55) | HTR6MAOAMAOB | |
| SCHEMBL2183807 | 0.83 | F10 (0.50) | HTR6F10MAOAMAOB | |
| SCHEMBL14334352 | 0.82 | HTR6 (0.66) | HTR6MAOAMAOB | |
| SCHEMBL14334461 | 0.81 | HTR6 (0.41) | HTR6F10MAOAMAOB | |
| SCHEMBL2184779 | 0.79 | F10 (0.40) | HTR6F10MAOAMAOBDRD1 | |
| SCHEMBL2184784 | 0.78 | GRM2 (0.41) | HTR6F10MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220079-A2 | SUBSTITUTED AMIDES, MANUFACTURING AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009063028-A2 | SUBSTITUTED AMIDES, MANUFACTURING AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-22 | — | — | WO | disclosed |