Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.52 |
| ▸ | HTR3B | O95264 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2421717 | 0.73 | MMP9 (0.43) | KMT2ANPC1RAB9A | |
| SCHEMBL22904365 | 0.72 | MMP9 (0.46) | NPC1RAB9A | |
| SCHEMBL2428253 | 0.72 | MMP9 (0.46) | NPC1RAB9A | |
| SCHEMBL31229951 | 0.71 | NPC1 (0.47) | GLAKMT2ANPC1RAB9A | |
| Benzoclidine SCHEMBL1542430 | 0.71 | GLA (0.74) | GLACHRNA7HTR3EHTR3BCHRNB2 | |
| Benzoclidine SCHEMBL342347 | 0.71 | GLA (0.74) | GLACHRNA7HTR3EHTR3BCHRNB2 | |
| Benzoclidine SCHEMBL1542330 | 0.71 | GLA (0.74) | GLACHRNA7HTR3EHTR3BCHRNB2 | |
| SCHEMBL3743481 | 0.69 | CHRM2 (0.71) | GLACHRNA7CHRM2CHRM1MEN1 | |
| SCHEMBL28413511 | 0.69 | HTT (0.40) | GLAHTR3AKMT2ANPC1RAB9A | |
| SCHEMBL14678608 | 0.69 | CHRNA7 (1.00) | GLACHRNA7HTR3EHTR3BCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723734-A1 | PROCESS FOR THE PREPARATION OF SOLIFENACIN AND SALTS THEREOF | Isochem (FR) | 2014-04-30 | — | — | EP | disclosed |
| WO-2012175119-A1 | PROCESS FOR THE PREPARATION OF SOLIFENACIN AND SALTS THEREOF | ISOCHEM (FR) | 2012-12-27 | — | — | WO | disclosed |