SCHEMBL2148267

SCHEMBL2148267

C/C=C\c1cccc(C(=O)Oc2ccccc2)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.53
ALOX15 P16050 2/20 0.53
HPGD P15428 2/20 0.53
MAPT P10636 5/20 0.50
KDM4E B2RXH2 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 2/20 0.43
NSD2 O96028 1/20 0.43
LMNA P02545 2/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
CHRM1 P11229 1/20 0.42
TBXA2R P21731 1/20 0.42
SLC6A2 P23975 1/20 0.42
PDE4A P27815 1/20 0.42
ADRA1A P35348 1/20 0.42
KDR P35968 1/20 0.42
SLC6A3 Q01959 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2148269 1.00 HSD17B10 (0.53) HSD17B10ALOX15HPGDMAPTKDM4E
Water SCHEMBL28394282 0.86 HSD17B10 (0.53) HSD17B10ALOX15HPGDMAPTKDM4E
SCHEMBL5087773 0.83 HSD17B10 (0.57) HSD17B10ALOX15HPGDMAPTKDM4E
SCHEMBL5712255 0.81 HSD17B10 (0.71) HSD17B10ALOX15HPGDMAPTKDM4E
SCHEMBL11130591 0.79 ALDH1A1 (0.53) HSD17B10ALOX15HPGDKDM4EALDH1A1
SCHEMBL11130587 0.79 ALDH1A1 (0.53) HSD17B10ALOX15HPGDKDM4EALDH1A1
SCHEMBL10966780 0.78 TSHR (0.54) HSD17B10ALOX15HPGDMAPTALDH1A1
SCHEMBL10966785 0.78 TSHR (0.54) HSD17B10ALOX15HPGDMAPTALDH1A1
SCHEMBL70410 0.77 HSD17B10 (0.61) HSD17B10ALOX15HPGDMAPTKDM4E
SCHEMBL70411 0.77 HSD17B10 (0.61) HSD17B10ALOX15HPGDMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977414-B2 Radiation-resistant resin composition and radiation-proof wire/cable FUJIKURA LTD. (JP) 2011-07-12 US disclosed