SCHEMBL14337339

SCHEMBL14337339

C/C(=N\c1ccccc1)c1ccc[nH]1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 2/20 0.52
NOS1 P29475 2/20 0.52
CYP1A2 P05177 1/20 0.47
SMN1; SMN2 Q16637 4/20 0.42
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
MEN1 O00255 4/20 0.40
MAPT P10636 4/20 0.40
KMT2A Q03164 4/20 0.40
GAA P10253 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
POLB P06746 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 2/20 0.39
ALOX12 P18054 1/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2491802 0.75
SCHEMBL3464105 0.75
SCHEMBL7099176 0.74
SCHEMBL28013846 0.73 NOS1 (0.47) NOS3NOS1SMN1; SMN2MEN1MAPT
SCHEMBL4253060 0.72 CYP1A2 (0.50) CYP1A2SMN1; SMN2RAB9ANPC1MEN1
SCHEMBL14337444 0.70 NOS1 (0.48) NOS3NOS1SMN1; SMN2RAB9ANPC1
SCHEMBL8155649 0.70 NOS3 (0.58) NOS3NOS1CYP1A2SMN1; SMN2RAB9A
SCHEMBL1890790 0.70 NOS3 (0.58) NOS3NOS1CYP1A2SMN1; SMN2RAB9A
SCHEMBL1890792 0.70 NOS3 (0.58) NOS3NOS1CYP1A2SMN1; SMN2RAB9A
SCHEMBL4263883 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
EP-1832609-A2 Process for producing a copolymer of a non-polar olefin and a polar olefin and the copolymer obtained thereby Mitsui Chemicals, Inc. (JP) 2007-09-12 EP disclosed