Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.58 |
| ▸ | NOS1 | P29475 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1890790 | 1.00 | NOS3 (0.58) | NOS3NOS1MEN1KMT2ALMNA | |
| SCHEMBL1890792 | 1.00 | NOS3 (0.58) | NOS3NOS1MEN1KMT2ALMNA | |
| SCHEMBL15073401 | 0.95 | NOS3 (0.52) | NOS3NOS1MEN1KMT2ALMNA | |
| SCHEMBL15073411 | 0.89 | NOS1 (0.56) | NOS3NOS1MEN1KMT2ALMNA | |
| SCHEMBL16382908 | 0.87 | CYP2D6 (0.53) | NOS3NOS1MEN1KMT2ALMNA | |
| SCHEMBL11421052 | 0.87 | CYP2D6 (0.53) | NOS3NOS1MEN1KMT2ALMNA | |
| SCHEMBL11421050 | 0.87 | CYP2D6 (0.53) | NOS3NOS1MEN1KMT2ALMNA | |
| SCHEMBL9302496 | 0.87 | ESR1 (0.53) | NOS3NOS1MEN1KMT2ALMNA | |
| SCHEMBL22594341 | 0.87 | CYP2D6 (0.63) | NOS3NOS1MEN1KMT2ALMNA | |
| SCHEMBL15073407 | 0.85 | LMNA (0.49) | NOS3NOS1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239391-B1 | 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1994-03-02 | — | — | EP | claimed |
| EP-0239391-A2 | 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-30 | — | — | EP | claimed |
| US-11673125-B2 | Metal oxide-supported earth-abundant metal catalysts for highly efficient organic transformations | THE UNIVERSITY OF CHICAGO (US) | 2023-06-13 | — | — | US | disclosed |
| US-11673125-B2 | Metal oxide-supported earth-abundant metal catalysts for highly efficient organic transformations | THE UNIVERSITY OF CHICAGO (US) | 2023-06-13 | — | — | US | disclosed |
| US-20220013729-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | LT MATERIALS CO., LTD. (KR) | 2022-01-13 | — | — | US | disclosed |
| EP-3227018-B1 | CHELATION DIRECTED C-H ACTIVATION REACTIONS CATALYZED BY SOLID-SUPPORTED PALLADIUM(II) CATALYSTS | UNIV VIRGINIA COMMONWEALTH (US) | 2021-06-30 | — | — | EP | disclosed |
| US-10953393-B2 | Stabilization of active metal catalysts at metal-organic framework nodes for highly efficient organic transformations | THE UNIVERSITY OF CHICAGO (US) | 2021-03-23 | — | — | US | disclosed |
| US-10953393-B2 | Stabilization of active metal catalysts at metal-organic framework nodes for highly efficient organic transformations | THE UNIVERSITY OF CHICAGO (US) | 2021-03-23 | — | — | US | disclosed |
| US-10910567-B2 | Double spiro-type compound and organic light emitting diode comprising same | LG CHEM, LTD. | 2021-02-02 | — | — | US | disclosed |
| US-20200324276-A1 | METAL OXIDE-SUPPORTED EARTH-ABUNDANT METAL CATALYSTS FOR HIGHLY EFFICIENT ORGANIC TRANSFORMATIONS | THE UNIVERSITY OF CHICAGO | 2020-10-15 | — | — | US | disclosed |
| EP-2892879-B1 | CATALYSTS BASED ON AMINO-SULFIDE LIGANDS FOR HYDROGENATION AND DEHYDROGENATION PROCESSES | GOUSSEV DMITRI (CA) | 2020-07-22 | — | — | EP | disclosed |
| US-20070073065-A1 | Substituted optically active disphosphine compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-03-29 | — | — | US | disclosed |
| US-7193092-B2 | Chiral diphosphorus compounds and their transition metal complexes | LANXESS DEUTSCHLAND GMBH (DE) | 2007-03-20 | — | — | US | disclosed |
| US-7193092-B2 | Chiral diphosphorus compounds and their transition metal complexes | LANXESS DEUTSCHLAND GMBH (DE) | 2007-03-20 | — | — | US | disclosed |
| EP-1286937-B1 | CHIRAL MONOPHOSPHITES AS LIGANDS FOR ASYMETRICAL HDROGENATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2007-03-14 | — | — | EP | disclosed |
| US-6072085-A | COMBINING SUBSTRATE IMINE, NUCLEOPHILIC ACTIVATOR, SILANE, METAL CATALYST, WHEREIN CATALYST CATALYZES REDUCTION OF IMINE BY HYDROSILATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-06-06 | — | — | US | disclosed |
| EP-0239391-B1 | 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-4871751-A | 1,2,6-Triphenyl-4(1H)-pyridinone derivatives, and their use as fungicides | KUMAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| US-4757081-A | Agriculture, horticulture | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0239391-A2 | 1,2,6-triphenyl-4(1H)-pyridinone and pyridinethione derivatives, production and uses thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10910567-B2 | Double spiro-type compound and organic light emitting diode comprising same | NR2E3, ALDH1A2, CRY1 | NOS3 2913/4885NOS1 2518/4885MEN1 1825/4885 |
| US-10953393-B2 | Stabilization of active metal catalysts at metal-organic framework nodes for highly efficient organic transformations | SBK1, SIK1, SIK2 | NOS3 619/4885NOS1 566/4885MEN1 1548/4885 |
| US-20070073065-A1 | Substituted optically active disphosphine compound | DHPS, DOHH, DHODH | NOS3 3260/4885NOS1 1968/4885MEN1 792/4885 |
| US-20220013729-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | CRY1, CYP1B1, CYP1A1 | NOS3 1089/4885NOS1 186/4885MEN1 700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.