SCHEMBL14337386

SCHEMBL14337386

Cc1cc(C)c(/C=N\c2cc(C(C)(C)C)cc(C(C)(C)C)c2O)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
POLB P06746 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CA2 P00918 2/20 0.43
TYR P14679 1/20 0.43
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
GAA P10253 2/20 0.38
HTT P42858 2/20 0.37
HSPA5 P11021 1/20 0.37
CYP2C9 P11712 4/20 0.37
CYP2C19 P33261 4/20 0.37
CYP1A2 P05177 2/20 0.37
HSD17B2 P37059 1/20 0.36
HIF1A Q16665 2/20 0.36
HSD17B10 Q99714 2/20 0.36
CYP2D6 P10635 1/20 0.36
PTGS2 P35354 4/20 0.36
ALOX5 P09917 3/20 0.36
PTGS1 P23219 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14337299 0.82 MEN1 (0.39) ALDH1A1POLBSMN1; SMN2CA2TYR
SCHEMBL14337294 0.80 DHODH (0.45) ALDH1A1POLBSMN1; SMN2CA2TYR
SCHEMBL14337334 0.77 CA2 (0.41) ALDH1A1POLBSMN1; SMN2CA2TYR
SCHEMBL14337524 0.77 SMN1; SMN2 (0.50) ALDH1A1POLBSMN1; SMN2CA2TYR
SCHEMBL14337302 0.76 MAPT (0.50) ALDH1A1POLBSMN1; SMN2CA2MEN1
SCHEMBL14337265 0.75 PTGS2 (0.47) ALDH1A1POLBCA2MEN1KMT2A
SCHEMBL12416798 0.75 ESRRG (0.42) ALDH1A1POLBSMN1; SMN2CA2TYR
SCHEMBL14337333 0.75 HTT (0.40) ALDH1A1POLBSMN1; SMN2CA2TYR
SCHEMBL14648328 0.74 PTGS2 (0.49) ALDH1A1POLBSMN1; SMN2CA2TYR
SCHEMBL16115892 0.74 PTGS2 (0.49) ALDH1A1POLBSMN1; SMN2CA2TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed