SCHEMBL14337299

SCHEMBL14337299

CC(C)(C)c1cc(/N=C\c2c(F)c(F)c(F)c(F)c2F)c(O)c(C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
GAA P10253 2/20 0.39
POLB P06746 2/20 0.39
HTT P42858 2/20 0.39
PTGS2 P35354 5/20 0.38
ALOX5 P09917 4/20 0.38
HSP90AA1 P07900 1/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 2/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
PTGS1 P23219 1/20 0.36
CA2 P00918 4/20 0.35
CA1 P00915 1/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14337524 0.85 SMN1; SMN2 (0.50) MEN1KMT2APOLBHTTPTGS2
SCHEMBL14337386 0.82 ALDH1A1 (0.43) MEN1KMT2AGAAPOLBHTT
SCHEMBL14337334 0.79 CA2 (0.41) MEN1KMT2AGAAPOLBHTT
SCHEMBL14337272 0.78 HSP90AA1 (0.38) MEN1KMT2APOLBHTTPTGS2
SCHEMBL14337265 0.78 PTGS2 (0.47) MEN1KMT2AGAAPOLBHTT
SCHEMBL12416798 0.78 ESRRG (0.42) MEN1KMT2AGAAPOLBHTT
SCHEMBL14337333 0.78 HTT (0.40) MEN1KMT2APOLBHTTPTGS2
SCHEMBL16361246 0.77 PTGS2 (0.41) MEN1KMT2AGAAPOLBHTT
SCHEMBL12416829 0.75 CA12 (0.53) MEN1KMT2AGAAPOLBHTT
SCHEMBL22080995 0.75 CA2 (0.43) MEN1KMT2AGAAPOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed