Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.48 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TFEB | P19484 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19343377 | 0.87 | ADORA2A (0.41) | MAPTLMNAKMT2AMEN1PLIN1 | |
| SCHEMBL15871330 | 0.87 | ADORA2A (0.41) | MAPTLMNAKMT2AMEN1PLIN1 | |
| SCHEMBL19330972 | 0.87 | ADORA2A (0.41) | MAPTLMNAKMT2AMEN1PLIN1 | |
| SCHEMBL29015396 | 0.87 | HTT (0.45) | MAPTLMNAKMT2AMEN1PLIN1 | |
| SCHEMBL31158626 | 0.86 | ALDH1A1 (0.38) | MAPTLMNAKMT2AMEN1PLIN1 | |
| SCHEMBL20536506 | 0.85 | MAPT (0.37) | MAPTLMNAKMT2AMEN1PLIN1 | |
| SCHEMBL16306341 | 0.85 | SMN1; SMN2 (0.45) | MAPTLMNAKMT2AMEN1PLIN1 | |
| SCHEMBL13629386 | 0.84 | MAPT (0.38) | MAPTLMNAKMT2AMEN1PLIN1 | |
| SCHEMBL24113246 | 0.84 | CTSL (0.38) | MAPTLMNAKMT2AMEN1PLIN1 | |
| SCHEMBL30310695 | 0.84 | CTSL (0.38) | MAPTLMNAKMT2AMEN1PLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307098-B2 | Indole derivatives and drugs containing the same | MEIJI DAIRIES CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |