Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23709914 | 0.92 | LMNA (0.47) | HTTHPGDALDH1A1LMNAKMT2A | |
| SCHEMBL23709923 | 0.91 | HTT (0.48) | HTTHPGDALDH1A1LMNAKMT2A | |
| SCHEMBL23709928 | 0.88 | LMNA (0.51) | HTTLMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL29015560 | 0.87 | HTT (0.49) | HTTHPGDALDH1A1LMNAKMT2A | |
| SCHEMBL14337628 | 0.87 | MAPT (0.48) | ALDH1A1LMNAKMT2AGAARAB9A | |
| SCHEMBL20536123 | 0.86 | L3MBTL1 (0.39) | HTTLMNAKMT2ACYP1A2CYP2C9 | |
| SCHEMBL20536125 | 0.86 | L3MBTL1 (0.39) | HTTLMNAKMT2ACYP1A2CYP2C9 | |
| SCHEMBL20536506 | 0.85 | MAPT (0.37) | HPGDALDH1A1LMNAKMT2AGAA | |
| SCHEMBL20535345 | 0.82 | MAPT (0.35) | HTTHPGDALDH1A1LMNAKMT2A | |
| SCHEMBL20535348 | 0.82 | MAPT (0.35) | HTTHPGDALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |