SCHEMBL1434037

SCHEMBL1434037

C[C@H](NC(=O)[C@@H](N)CC(=O)O)C(=O)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 4/20 0.45
▸ S1PR1 P21453 1/20 0.41
▸ S1PR3 Q99500 1/20 0.41
▸ SLC1A3 P43003 1/20 0.40
▸ METAP2 P50579 1/20 0.40
▸ MAPK1 P28482 1/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ ATM Q13315 1/20 0.39
▸ ELANE P08246 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ MTNR1A P48039 3/20 0.38
▸ MTNR1B P49286 3/20 0.38
▸ LNPEP Q9UIQ6 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28123995 0.85 CTSC (0.52) —
SCHEMBL27936797 0.84 CTRB1 (0.48) LTA4HSLC1A3METAP2MAPK1L3MBTL1
SCHEMBL31539992 0.82 LTA4H (0.53) LTA4HMETAP2ATMMAPT
SCHEMBL7782886 0.80 ATM (0.45) LTA4HSLC1A3L3MBTL1ATMELANE
SCHEMBL7782885 0.80 ATM (0.45) LTA4HSLC1A3L3MBTL1ATMELANE
Benzaldehyde SCHEMBL11058691 0.79 MAPT (0.44) LTA4HMETAP2MAPK1L3MBTL1MAPT
SCHEMBL10748731 0.79 BIRC2 (0.42) LTA4HS1PR1S1PR3METAP2L3MBTL1
SCHEMBL27524339 0.79 BIRC2 (0.42) LTA4HS1PR1S1PR3METAP2L3MBTL1
SCHEMBL10700935 0.79 BIRC2 (0.42) LTA4HS1PR1S1PR3METAP2L3MBTL1
SCHEMBL27183071 0.78 MTNR1A (0.62) LTA4HS1PR1S1PR3MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 350 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1163221-C Powdered masking agent for masking taste of drugs �˿�˹�����ﻯѧ��Ʒ��ҵ�ɷ����޹� 2004-08-25 — — CN claimed
CN-1285740-A Powdered masking agent for masking taste of drugs PANCOSMA SA POUR L IND DES PRO (CH) 2001-02-28 — — CN claimed
WO-2024148282-A1 ENZYME BASED COMPOSITIONS AND METHODS FOR REMOVING DENTAL CALCULI PONTIS BIOLOGICS, INC. (US) 2024-07-11 — — WO disclosed
US-20240033288-A1 COMPOSITIONS AND METHODS FOR DENTAL MINERALIZATION THE UNIVERSITY OF MELBOURNE (AU) 2024-02-01 — — US disclosed
EP-4311576-A2 TREATMENT FOR GINGIVITIS The University of Melbourne (AU) 2024-01-31 — — EP disclosed
US-20240016836-A1 TREATMENT FOR GINGIVITIS THE UNIVERSITY OF MELBOURNE (AU) 2024-01-18 — — US disclosed
EP-3595615-B1 TREATMENT FOR GINGIVITIS UNIV MELBOURNE (AU) 2024-01-10 — — EP disclosed
US-20240000671-A1 FLUORIDE COMPOSITION AND METHODS FOR DENTAL MINERALIZATION THE UNIVERSITY OF MELBOURNE (AU) 2024-01-04 — — US disclosed
US-20230404867-A1 STABILIZED STANNOUS COMPOSITIONS THE UNIVERSITY OF MELBOURNE (AU) 2023-12-21 — — US disclosed
US-20230374081-A1 PREVENTION, TREATMENT AND DIAGNOSIS OF P.GINGIVALIS INFECTION ORAL HEALTH AUSTRALIA PTY LTD (AU) 2023-11-23 — — US disclosed
US-11717536-B2 Treatment for periodontitis THE UNIVERSITY OF MELBOURNE (AU) 2023-08-08 — — US disclosed
US-4808401-A INHIBITION OF SALIVARY PHOSPHATASES BY POLYMERIC CARBOXYLATES AND/OR THEIR ALKALI METAL OR AMMONIUM DERIVATIVES; TOOTHPASTE COLGATE-PALMOLIVE COMPANY (US) 1989-02-28 — — US disclosed
US-4808400-A ANTICAVITY AND INHIBITING SALIVARY ENZYMATIC HYDROLYSIS DENTIFRICES COLGATE-PALMOLIVE COMPANY (US) 1989-02-28 — — US disclosed
US-4806340-A MIXTURE OF ALKALI METAL PYROPHOSPHATE, FLUORINE, AND ANIONIC POLYMER COLGATE-PALMOLIVE COMPANY (US) 1989-02-21 — — US disclosed
US-4806342-A INHIBITING ENZYMATIC HYTDROLYSIS OF POLYPHOSPHATE SALTS; FLUORIDE SOURCE AND ANIONIC POLYMERIC CARBOXYLATE COLGATE-PALMOLIVE COMPANY (US) 1989-02-21 — — US disclosed
US-4627977-A SODIUM FLUORIDE, POLYPHOSPHATE, SALT OF CARBOXYLATED POLYMER COLGATE-PALMOLIVE COMPANY (US) 1986-12-09 — — US disclosed
US-4590064-A PHOSPHONOFORMIC ACID OR SALT PLUS FLUORIDE COLGATE-PALMOLIVE COMPANY (US) 1986-05-20 — — US disclosed
US-4474750-A Anticalculus oral composition COLGATE-PALMOLIVE COMPANY (US) 1984-10-02 — — US disclosed
EP-0099960-A1 Process for the preparation of lower alkyl esters of N-L-alpha-aspartyl-L-phenyl alanine, and intermediates for their manufacture EPROVA AG Forschungsinstitut (CH) 1984-02-08 — — EP disclosed
US-4339431-A Anticalculus oral composition COLGATE-PALMOLIVE COMPANY (US) 1982-07-13 — — US disclosed
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