Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 17/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 9/20 | 0.45 |
| ▸ | PGR | P06401 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3538023 | 0.90 | POLB (0.45) | NR3C1NR3C2PGRPOLBNPSR1 | |
| SCHEMBL3954561 | 0.89 | NR3C1 (0.50) | NR3C1NR3C2PGRPOLBNPSR1 | |
| SCHEMBL1634191 | 0.87 | NR3C1 (0.58) | NR3C1NR3C2PGR | |
| SCHEMBL5644117 | 0.84 | FBP1 (0.43) | NR3C1NR3C2PGRPOLBNPSR1 | |
| SCHEMBL3957797 | 0.81 | NR3C1 (0.43) | NR3C1NR3C2PGR | |
| SCHEMBL5642117 | 0.80 | POLB (0.48) | NR3C1NR3C2PGRPOLBNPSR1 | |
| SCHEMBL5865883 | 0.78 | FBP1 (0.40) | NR3C2PGRPOLBNPSR1CYP3A4 | |
| SCHEMBL3950922 | 0.77 | POLB (0.38) | NR3C1NR3C2PGRPOLBNPSR1 | |
| SCHEMBL331835 | 0.76 | ALDH1A1 (0.45) | NR3C1NR3C2PGRPOLBNPSR1 | |
| SCHEMBL3957430 | 0.76 | NR3C1 (0.51) | NR3C1NR3C2PGRPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490062-B1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMA (US) | 2007-12-19 | — | — | EP | disclosed |