Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | BACE1 | P56817 | 4/20 | 0.56 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.56 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.54 |
| ▸ | FURIN | P09958 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | TFPI | P10646 | 1/20 | 0.52 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.51 |
| ▸ | GNPAT | O15228 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29493698 | 0.87 | CTSD (0.56) | CTSBCTSKGNPATPSEN1PSEN2 | |
| SCHEMBL31554789 | 0.86 | BACE1 (0.57) | BACE1BACE2OPRK1 | |
| SCHEMBL31114998 | 0.85 | NPY4R (0.58) | BACE1BACE2KISS1RFURINTFPI | |
| SCHEMBL28182078 | 0.85 | BACE1 (0.56) | BACE1BACE2 | |
| SCHEMBL28182080 | 0.85 | BACE1 (0.56) | BACE1BACE2 | |
| SCHEMBL5576870 | 0.84 | OPRK1 (0.63) | BACE1BACE2OPRK1GNPAT | |
| SCHEMBL5576866 | 0.84 | OPRK1 (0.63) | BACE1BACE2OPRK1GNPAT | |
| SCHEMBL17935594 | 0.84 | BACE1 (0.57) | BACE1BACE2OPRK1 | |
| SCHEMBL28891604 | 0.84 | BACE1 (0.56) | CTSBBACE1BACE2OPRK1 | |
| SCHEMBL28891603 | 0.84 | BACE1 (0.56) | CTSBBACE1BACE2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145589-A1 | PEPTIDES THAT ARE CAPABLE OF BINDING TO AMYLOID-BETA PEPTIDE. | ARVIDSSON PER (SE) | 2007-12-21 | — | — | WO | disclosed |