Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 6/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14343099 | 1.00 | ITGB3 (0.45) | ITGB3ITGA2BCTSSCTSKHDAC8 | |
| SCHEMBL14405381 | 0.90 | CACNA1B (0.41) | ITGB3ITGA2BCTSSCTSKHDAC8 | |
| SCHEMBL16173548 | 0.89 | ITGB3 (0.49) | ITGB3ITGA2BCTSSCTSKHDAC8 | |
| SCHEMBL16173550 | 0.89 | ITGB3 (0.49) | ITGB3ITGA2BCTSSCTSKHDAC8 | |
| SCHEMBL14343090 | 0.89 | ITGB3 (0.49) | ITGB3ITGA2BCTSSCTSKHDAC8 | |
| SCHEMBL14343036 | 0.89 | ITGB3 (0.49) | ITGB3ITGA2BCTSSCTSKHDAC8 | |
| SCHEMBL16173579 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BCTSSCTSKHDAC8 | |
| SCHEMBL16173577 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BCTSSCTSKHDAC8 | |
| SCHEMBL14343166 | 0.87 | CTSS (0.56) | ITGB3ITGA2BCTSSCTSKHDAC8 | |
| SCHEMBL14343029 | 0.87 | CTSS (0.56) | ITGB3ITGA2BCTSSCTSKHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140309424-A1 | DIRECT SYNTHESIS OF 18F-FLUOROMETHOXY COMPOUNDS FOR PET IMAGING AND THE PROVISION OF NEW PRECURSORS FOR DIRECT RADIOSYNTHESIS OF PROTECTED DERIVATIVES OF O-([18F] FLUOROMETHYL) TYROSINE | PIRAMAL IMAGING SA (CH) | 2014-10-16 | — | — | US | disclosed |
| US-20140309424-A1 | DIRECT SYNTHESIS OF 18F-FLUOROMETHOXY COMPOUNDS FOR PET IMAGING AND THE PROVISION OF NEW PRECURSORS FOR DIRECT RADIOSYNTHESIS OF PROTECTED DERIVATIVES OF O-([18F] FLUOROMETHYL) TYROSINE | PIRAMAL IMAGING SA (CH) | 2014-10-16 | — | — | US | disclosed |
| US-20140309424-A1 | DIRECT SYNTHESIS OF 18F-FLUOROMETHOXY COMPOUNDS FOR PET IMAGING AND THE PROVISION OF NEW PRECURSORS FOR DIRECT RADIOSYNTHESIS OF PROTECTED DERIVATIVES OF O-([18F] FLUOROMETHYL) TYROSINE | PIRAMAL IMAGING SA (CH) | 2014-10-16 | — | — | US | disclosed |
| EP-2540710-A1 | New precursors for direct radiosynthesis of protected derivatives of O-([18F]Fluoromethyl) tyrosine | Bayer Schering Pharma Aktiengesellschaft (DE) | 2013-01-02 | — | — | EP | disclosed |
| EP-2540710-A1 | New precursors for direct radiosynthesis of protected derivatives of O-([18F]Fluoromethyl) tyrosine | Bayer Schering Pharma Aktiengesellschaft (DE) | 2013-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309424-A1 | DIRECT SYNTHESIS OF 18F-FLUOROMETHOXY COMPOUNDS FOR PET IMAGING AND THE PROVISION OF NEW PRECURSORS FOR DIRECT RADIOSYNTHESIS OF PROTECTED DERIVATIVES OF O-([18F] FLUOROMETHYL) TYROSINE | TH, TYR, FTO | ITGB3 2717/4885ITGA2B 3431/4885CTSS 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.