Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485162 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2MAPTALDH1A1GAAPOLB | |
| SCHEMBL14344751 | 0.79 | CPN1 (0.41) | SMN1; SMN2MAPTALDH1A1GAAPOLB | |
| SCHEMBL13270668 | 0.77 | TP53 (0.40) | SMN1; SMN2MAPTALDH1A1GAAPOLB | |
| SCHEMBL24684871 | 0.77 | KMT2A (0.36) | SMN1; SMN2RAB9ATP53LMNA | |
| SCHEMBL669086 | 0.77 | — | — | |
| SCHEMBL14448370 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTALDH1A1GAAPOLB | |
| SCHEMBL2030080 | 0.76 | GAA (0.55) | SMN1; SMN2ALDH1A1GAARAB9ACYP2C19 | |
| SCHEMBL4272598 | 0.76 | GAA (0.33) | SMN1; SMN2GAACYP2C19 | |
| SCHEMBL587681 | 0.75 | LMNA (0.53) | SMN1; SMN2MAPTALDH1A1GAAPOLB | |
| SCHEMBL310852 | 0.75 | HRH3 (0.60) | SMN1; SMN2MAPTALDH1A1HRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103534265-A | Cyclic peptides with an anti-neoplasic and anti-angiogenic activity | CT INGENIERIA GENETICA BIOTECH | 2014-01-22 | — | — | CN | claimed |
| CN-103534265-A | Cyclic peptides with an anti-neoplasic and anti-angiogenic activity | CT INGENIERIA GENETICA BIOTECH | 2014-01-22 | — | — | CN | disclosed |