Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.59 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKLR | P30613 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28495378 | 0.94 | PKM (0.53) | PKMPTPRZ1HSD11B1MMP13CA1 | |
| SCHEMBL11507063 | 0.83 | PTPRZ1 (0.61) | PTPRZ1NPC1RAB9AKIF11ALDH1A1 | |
| SCHEMBL14227521 | 0.82 | PKM (0.57) | PKMHSD11B1MMP13CA1CA2 | |
| SCHEMBL31420183 | 0.81 | PKM (0.52) | PKMHSD11B1MMP13CA1CA2 | |
| SCHEMBL754571 | 0.81 | PKM (0.61) | PKMMMP13CA1CA2GAA | |
| SCHEMBL752793 | 0.81 | PKM (0.61) | PKMMMP13CA1CA2GAA | |
| SCHEMBL12725103 | 0.81 | PKM (0.61) | PKMHSD11B1MMP13CA1CA2 | |
| SCHEMBL91977 | 0.81 | PTPRZ1 (0.59) | PTPRZ1KMT2AKIF11ALDH1A1LMNA | |
| SCHEMBL2330600 | 0.81 | MEN1 (0.50) | PKMPTPRZ1KMT2AALDH1A1PTGS2 | |
| SCHEMBL24010109 | 0.80 | PKM (0.55) | PKMHSD11B1MMP13CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007139729-A1 | NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE | MERCK & CO., INC. (US) | 2007-12-06 | — | — | WO | disclosed |