Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 8/20 | 0.42 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11507063 | 0.84 | PTPRZ1 (0.61) | PTPRZ1LMNASMN1; SMN2MAPK1HTT | |
| SCHEMBL14345059 | 0.81 | PKM (0.59) | PTPRZ1LMNASMN1; SMN2MAPK1HTT | |
| SCHEMBL8941529 | 0.79 | PTPRZ1 (0.56) | PTPRZ1LMNASMN1; SMN2MAPK1HTT | |
| Sulfuric Acid SCHEMBL28495378 | 0.76 | PKM (0.53) | PTPRZ1HTTALDH1A1KIF11KMT2A | |
| SCHEMBL20314687 | 0.76 | PTPRZ1 (0.67) | PTPRZ1LMNASMN1; SMN2MAPK1HTT | |
| SCHEMBL19389583 | 0.76 | PTPRZ1 (0.67) | PTPRZ1LMNASMN1; SMN2MAPK1HTT | |
| SCHEMBL11060588 | 0.76 | PTPRZ1 (0.53) | PTPRZ1LMNAMAPK1HTTALDH1A1 | |
| SCHEMBL6000294 | 0.75 | PTPRZ1 (1.00) | PTPRZ1PTPN1 | |
| SCHEMBL1886221 | 0.75 | MAPT (0.65) | PTPRZ1LMNASMN1; SMN2ALDH1A1KIF11 | |
| SCHEMBL8941541 | 0.75 | PTPRZ1 (0.51) | PTPRZ1SMN1; SMN2HTTALDH1A1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |