Sulfuric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CALCRL CHRM1 CHRM2 CHRM3 F2R MAOA MAOB MAP2K1 MAP2K2 NTRK1 NTRK2 NTRK3 OPRD1 OPRK1 OPRM1 P2RY12 PKLR SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SLC18A2 SLC6A2 SLC6A3 TLR7 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 dacA dacB dacC folA ftsI mrcA mrcB mrdA pol rplA rplB rplC rplD rplE rplF rplI rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmB1 rpmB2 rpmC rpmD rpmE rpmE2 rpmF rpmG rpmG1 rpmG2 rpmH rpmI rpmJ rpmJ2 rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsR1 rpsR2 rpsS rpsT rpsU rpsZ ykgM ykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	PKLR known ✓	P30613	1/20	0.44

▸	PKM	P14618	4/20	0.53

▸	PTPRZ1	P23471	1/20	0.53

▸	HSD11B1	P28845	1/20	0.51

▸	MMP9	P14780	7/20	0.50

▸	MMP13	P45452	7/20	0.50

▸	MMP1	P03956	6/20	0.50

▸	GAA	P10253	2/20	0.50

▸	CA1	P00915	1/20	0.50

▸	CA2	P00918	1/20	0.50

▸	MMP2	P08253	1/20	0.50

▸	MMP8	P22894	1/20	0.50

▸	F2	P00734	2/20	0.46

▸	PRSS1	P07477	2/20	0.46

▸	PRSS2	P07478	2/20	0.46

▸	PRSS3	P35030	2/20	0.46

▸	ALDH1A1	P00352	1/20	0.46

▸	NPC1	O15118	1/20	0.44

▸	RAB9A	P51151	1/20	0.44

▸	KMT2A	Q03164	1/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14345059	0.94	PKM (0.59)	PKMPTPRZ1HSD11B1MMP9MMP13
SCHEMBL31420185	0.79	PKM (0.50)	PKMPTPRZ1HSD11B1MMP9MMP13
SCHEMBL11507063	0.78	PTPRZ1 (0.61)	PTPRZ1ALDH1A1NPC1RAB9AHTT
SCHEMBL14227521	0.77	PKM (0.57)	PKMHSD11B1MMP9MMP13MMP1
Trifluoromethanesulfonic Acid SCHEMBL23045290	0.76	PKM (0.47)	PKMHSD11B1MMP9MMP13MMP1
SCHEMBL31420183	0.76	PKM (0.52)	PKMHSD11B1MMP9MMP13MMP1
SCHEMBL1886221	0.76	MAPT (0.65)	PKMPTPRZ1GAAALDH1A1KMT2A
SCHEMBL752793	0.76	PKM (0.61)	PKMMMP9MMP13MMP1GAA
SCHEMBL12725103	0.76	PKM (0.61)	PKMHSD11B1MMP9MMP13MMP1
SCHEMBL754571	0.76	PKM (0.61)	PKMMMP9MMP13MMP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-110483347-B	Process for preparing substituted trifluoromethylsulfanyl benzenes from substituted anilines	天津师范大学	2021-03-16	—	—	CN	claimed
CN-110483350-B	Process for converting substituted phenyldiazonium salts into trifluoromethylsulfanylbenzenes	天津师范大学	2021-01-05	—	—	CN	claimed
CN-110483347-B	Process for preparing substituted trifluoromethylsulfanyl benzenes from substituted anilines	天津师范大学	2021-03-16	—	—	CN	disclosed
CN-110483347-B	Process for preparing substituted trifluoromethylsulfanyl benzenes from substituted anilines	天津师范大学	2021-03-16	—	—	CN	disclosed
CN-110483350-B	Process for converting substituted phenyldiazonium salts into trifluoromethylsulfanylbenzenes	天津师范大学	2021-01-05	—	—	CN	disclosed
CN-110483350-B	Process for converting substituted phenyldiazonium salts into trifluoromethylsulfanylbenzenes	天津师范大学	2021-01-05	—	—	CN	disclosed