Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.60 |
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6107601 | 0.86 | RAB9A (0.60) | RAB9ANPC1TP53RXFP1KMT2A | |
| SCHEMBL14366548 | 0.85 | PKM (0.52) | RAB9ANPC1TP53RXFP1NPSR1 | |
| SCHEMBL2989712 | 0.85 | KMT2A (0.55) | RAB9ANPC1MAPK1TP53RXFP1 | |
| SCHEMBL2978677 | 0.85 | KMT2A (0.58) | RAB9ANPC1MAPK1TP53RXFP1 | |
| SCHEMBL14345277 | 0.85 | RAB9A (0.64) | RAB9ANPC1MAPK1TP53RXFP1 | |
| SCHEMBL890667 | 0.84 | RAB9A (0.57) | RAB9ANPC1MAPK1TP53MITF | |
| SCHEMBL27453745 | 0.82 | NPC1 (0.72) | RAB9ANPC1TP53RXFP1KMT2A | |
| SCHEMBL14345211 | 0.82 | ALDH1A1 (0.59) | RAB9ANPC1MAPK1TP53KMT2A | |
| SCHEMBL14345243 | 0.81 | PKM (0.48) | RAB9ANPC1TP53RXFP1NPSR1 | |
| SCHEMBL890832 | 0.78 | KDM4E (0.73) | RAB9ANPC1MAPK1TP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |