Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | PPARG | P37231 | 3/20 | 0.65 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.65 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.65 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.58 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423857 | 0.90 | RAB9A (0.63) | RAB9AALDH1A1PPARGNCOA2NCOA1 | |
| SCHEMBL31423859 | 0.90 | RAB9A (0.63) | RAB9AALDH1A1PPARGNCOA2NCOA1 | |
| SCHEMBL14345627 | 0.83 | RAB9A (0.57) | RAB9AALDH1A1PPARGNCOA2NCOA1 | |
| SCHEMBL5360478 | 0.81 | GAA (0.69) | RAB9AALDH1A1PPARGNCOA2NCOA1 | |
| SCHEMBL14345712 | 0.78 | CCNA2 (0.61) | ALDH1A1PPARGNCOA2NCOA1NCOA3 | |
| SCHEMBL5356543 | 0.77 | ADORA2B (0.65) | RAB9AALDH1A1PPARGNCOA2NCOA1 | |
| SCHEMBL15064944 | 0.74 | KMT2A (0.70) | RAB9AALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL31423860 | 0.74 | ADORA2B (0.54) | RAB9AALDH1A1PPARGNCOA2NCOA1 | |
| SCHEMBL31423858 | 0.74 | TP53 (0.65) | RAB9AALDH1A1PPARGNCOA2NCOA1 | |
| SCHEMBL31415156 | 0.74 | CDK5 (1.00) | RAB9AKMT2AMEN1NPC1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | disclosed |