Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 2/20 | 0.61 |
| ▸ | CDK2 | P24941 | 2/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5402536 | 0.84 | LMNA (0.55) | CCNA2CDK2ADORA2BSMN1; SMN2LMNA | |
| SCHEMBL14345621 | 0.84 | DHODH (0.57) | CCNA2CDK2ADORA2BSMN1; SMN2LMNA | |
| SCHEMBL5330484 | 0.80 | LMNA (0.56) | CCNA2CDK2ADORA2BSMN1; SMN2LMNA | |
| SCHEMBL5356543 | 0.79 | ADORA2B (0.65) | CDK2ADORA2BSMN1; SMN2LMNAALOX5 | |
| SCHEMBL4402464 | 0.78 | ADORA2B (0.86) | CCNA2CDK2ADORA2BSMN1; SMN2LMNA | |
| SCHEMBL14345713 | 0.78 | RAB9A (0.65) | ADORA2BSMN1; SMN2LMNAALOX5PTGS2 | |
| SCHEMBL5418954 | 0.78 | LMNA (0.48) | CCNA2CDK2ADORA2BSMN1; SMN2LMNA | |
| SCHEMBL1883114 | 0.77 | MAPT (0.66) | ADORA2BSMN1; SMN2LMNADHODHALDH1A1 | |
| SCHEMBL5355961 | 0.77 | DHODH (0.53) | ADORA2BSMN1; SMN2LMNADHODHALDH1A1 | |
| SCHEMBL31423856 | 0.77 | ADORA2B (0.74) | CCNA2CDK2ADORA2BSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | disclosed |