Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.44 |
| ▸ | DRD3 | P35462 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843665 | 0.90 | CHRM2 (0.48) | DRD2DRD3ALOX15CHRM2CHRM1 | |
| SCHEMBL3848987 | 0.88 | DRD2 (0.50) | DRD2DRD3ALOX15CHRM2CHRM1 | |
| SCHEMBL3848755 | 0.87 | DRD2 (0.45) | DRD2DRD3CHRM2CHRM1DRD1 | |
| SCHEMBL3845650 | 0.86 | NOTUM (0.51) | DRD2DRD3LMNAMAPT | |
| SCHEMBL3845301 | 0.86 | DRD2 (0.50) | DRD2DRD3CHRM2CHRM1DRD4 | |
| SCHEMBL3847430 | 0.85 | CHRM4 (0.54) | DRD2DRD3CHRM2CHRM1 | |
| SCHEMBL3851253 | 0.84 | DRD2 (0.52) | DRD2DRD3DRD4MEN1LMNA | |
| Hydrochloric Acid SCHEMBL28782169 | 0.84 | CHRM4 (0.54) | DRD2DRD3CHRM2CHRM1 | |
| SCHEMBL3846117 | 0.84 | DRD2 (0.52) | DRD2DRD3 | |
| SCHEMBL3846127 | 0.83 | CHRM4 (0.48) | DRD2DRD3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007148208-A2 | CARBONYLATED (AZA) CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET (FR) | 2007-12-27 | — | — | WO | disclosed |