SCHEMBL3843665

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3845301	0.91	DRD2 (0.50)	CHRM2CHRM1DRD2DRD3LMNA
	SCHEMBL3848987	0.91	DRD2 (0.50)	CHRM2CHRM1ALOX15DRD2DRD3
	SCHEMBL3848755	0.90	DRD2 (0.45)	CHRM2CHRM1DRD2DRD3MEN1
	SCHEMBL14346809	0.90	DRD2 (0.44)	CHRM2CHRM1ALOX15DRD2DRD3
	SCHEMBL3845650	0.89	NOTUM (0.51)	DRD2DRD3LMNAMAPT
	SCHEMBL3846127	0.88	CHRM4 (0.48)	CHRM2CHRM1DRD2DRD3
	SCHEMBL3847430	0.87	CHRM4 (0.54)	CHRM2CHRM1DRD2DRD3
	SCHEMBL3851253	0.87	DRD2 (0.52)	DRD2DRD3MEN1KMT2ALMNA
	Hydrochloric Acid SCHEMBL28782169	0.87	CHRM4 (0.54)	CHRM2CHRM1DRD2DRD3
	SCHEMBL3843632	0.85	DRD2 (0.51)	DRD2DRD3MAPTHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.