SCHEMBL3845650

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3846267	0.90	DRD2 (0.48)	NOTUMDRD2DRD3LMNATP53
	SCHEMBL3843665	0.89	CHRM2 (0.48)	DRD2DRD3LMNAMAPT
	SCHEMBL3846120	0.89	NOTUM (0.53)	NOTUMLMNATP53MAPT
	SCHEMBL3848987	0.87	DRD2 (0.50)	DRD2DRD3LMNAMAPT
	SCHEMBL3848755	0.86	DRD2 (0.45)	DRD2DRD3LMNAMAPT
	SCHEMBL14346809	0.86	DRD2 (0.44)	DRD2DRD3LMNAMAPT
	SCHEMBL3845301	0.85	DRD2 (0.50)	DRD2DRD3LMNAMAPT
	SCHEMBL3847606	0.84	DRD2 (0.43)	DRD2DRD3
	SCHEMBL3847430	0.84	CHRM4 (0.54)	DRD2DRD3
	SCHEMBL3853546	0.84	SLC6A2 (0.55)	NOTUMDRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.